Compatibility «Clarithromycin» and «Enfuvirtide»
Between «Clarithromycin» and «Enfuvirtide» found 1 dangerous and 3 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Enfuvirtide |
✘Clarithromycin Analogs | |
✘Enfuvirtide Analogs |
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Interactions Clarithromycin with Enfuvirtide
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Dangerous interactions
In this regard, the simultaneous use of lansoprazole with antiviral drugs such as atazanavir and nelfinavir is contraindicated. -
Negative interactions
Similar dose adjustments should be considered in patients with reduced renal function if ritonavir is used as a pharmacokinetic 'booster' when using other HIV protease inhibitors, including atazanavir and saquinavir (see subsection 'Bidirectional drug interaction'). With the simultaneous use of lansoprazole and some antiviral drugs, such as atazanavir and nelfinavir, against the background of therapy with lansoprazole, there is a decrease in their concentration in blood serum. Enfuvirtide at the recommended dose of 90 mg 2 times a day does not inhibit the metabolism of substrates of the isoenzyme CYP3A4 (dapsone), CYP2D6 (debrisochine), CYP1A2 (caffeine), CYP2C19 (mephenytoin) and CYP2E1 (chlorzoxazone). -
Positive interactions
An increase in the pH value during therapy with lansoprazole may affect the absorption of antiviral drugs. -
Unclear interactions
HIV protease inhibitors. Lansoprazole has been shown to interact with some antiviral drugs.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
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Additional information
- Kiberis checks interactions and evaluates drug compatibility online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,974,420 possible combinations of drugs and their components were found 412,510 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-05-02
Category - medicine