Compatibility «Ciclosporin» and «Eltrombopag»
Between «Ciclosporin» and «Eltrombopag» found 4 negative interactions, they should be taken with caution. the doctor may need to adjust the dosage.
Interaction tableCompare |
Eltrombopag |
| ✘Ciclosporin Analogs | |
| ✘Eltrombopag Analogs |
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Interactions Ciclosporin with Eltrombopag
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Negative interactions
- A decrease in eltrombopag exposure was noted when concomitantly administered with 200 and 600 mg of cyclosporine (BCRP inhibitor), which was not regarded as clinically significant.
- The number of platelets should be monitored weekly for 2-3 weeks against the background of simultaneous use of elthrombopag with cyclosporine.
- A single application of 50 mg of elthrombopag with cyclosporine at a dose of 200 mg (BCRP inhibitor) led to a decrease in max and AUC of elthrombopag by 25 and 18%, respectively.
- Simultaneous administration of 600 mg of cyclosporine resulted in a decrease in Cmax and AUC of elthrombopagus by 39 and 24%, respectively.
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Unclear interactions
- Cyclosporine.
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Negative interactions
Decoding the colors of interactions and contraindications
| Dangerous | — | a pronounced negative interaction or contraindication. |
| Negative | — | negative interaction or side effect that may reduce effectiveness. |
| Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
| No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
| Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
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- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,994,378 possible combinations of drugs and their components were found 412,530 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-12-19
Category - medicine