Compatibility «Phenobarbital» and «Gabapentin»
Between «Phenobarbital» and «Gabapentin» found 1 dangerous and 2 negative interactions, joint admission is not recommended without consulting a doctor.
Interaction tableCompare |
Gabapentin |
✘Phenobarbital Analogs | |
✘Gabapentin Analogs |
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Interactions Phenobarbital with Gabapentin
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Dangerous interactions
When used simultaneously with other drugs that depress the central nervous system (in pm sedatives, hypnotics, some antihistamines, anxiolytics), and alcohol, an additive depressive effect is possible. -
Negative interactions
The same effects are observed when taken simultaneously with other CNS depressants. Since false positive test results were obtained using the Ames N-Multistix SG test strip when gabapentin was added to other antiepileptic drugs, a more specific sulfosalicylic acid precipitation procedure is recommended to determine the presence of protein in urine. -
No interactions
The pharmacokinetic parameters of phenobarbital or gabapentin (300 mg 3 times a day, n= 12) did not differ depending on whether these drugs were used separately or together. Gabapentin does not undergo significant metabolism and does not affect the metabolism of antiepileptic drugs usually taken simultaneously. -
Unclear interactions
Phenobarbital. Other antiepileptic drugs.
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Dangerous interactions
Decoding the colors of interactions and contraindications
Dangerous | — | a pronounced negative interaction or contraindication. |
Negative | — | negative interaction or side effect that may reduce effectiveness. |
Positive | — | the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug. |
No | — | the drugs do NOT interact, which is separately indicated in the instructions. |
Unclear | — | the system failed to pre-assess the danger. |
Video instruction
Additional information
- Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
- Why do I need to
- Avoid dangerous prescriptions for your patients.
- Check the contraindications.
- Evaluate the safety of therapy in the treatment of children.
- See the compatibility of drugs with alcohol (enter it as a drug).
- Point the doctor to the found interaction - you may need to adjust the therapy.
- The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
- The article is written: artificial intelligence Kiberis
- Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
- Total analyzed: 169,978,048 possible combinations of drugs and their components were found 412,514 interacting combinations.
- Medicine section: Standard evidence-based medicine
- The date of the last update of the interaction database: 2024-06-13
Category - medicine