Compatibility «Enalapril» and «Fokusin»

• Interactions Enalapril with Fokusin

  • Dangerous interactions
    • ⓘ In three studies in patients with hypertension (47-79 years old), whose blood pressure was controlled by stable doses of nifedipine, atenolol or enalapril for at least 3 months, tamsulosin intake at a dose of 0.4 mg for 7 days, and then at a dose of 0.8 mg for another 7 days (n=8 in each study) was not It had a clinically significant effect on blood pressure and heart rate compared with placebo (n=4 in each study).
  • Negative interactions
    • ⓘ The possibility of hypotensive effects when using enalapril can be minimized by stopping the diuretic or increasing salt intake before starting treatment with enalapril.
    • ⓘ Other antihypertensive drugs.
    • ⓘ When using enalapril simultaneously with other antihypertensive agents, especially with diuretics, an increased antihypertensive effect may be observed.
    • ⓘ The simultaneous use of enalapril with alpha‑blockers, beta‑blockers and ganglioblockers should be carried out under careful medical supervision.
    • ⓘ NSAIDs, including selective COX‑2 inhibitors and acetylsalicylic acid in doses of 3 g/day and above, can reduce the antihypertensive effect of diuretics and other antihypertensive agents.
    • ⓘ Blood pressure should be carefully monitored and, if necessary, the dose of antihypertensive drugs should be adjusted.
    • ⓘ Alpha-blockers and PDE-5 inhibitors are vasodilators that reduce blood pressure.
  • No interactions
    • ⓘ When tamsulosin was co-administered with atenolol, enalapril, or theophylline, there were no signs of drug interaction.
    • ⓘ There was no clinically significant drug interaction with the combined use of tamsulosin at a dose of 0.4 or 0.8 mg and nifedipine, atenolol, enalapril, digoxin, furosemide or theophylline.
    • ⓘ When tamsulosin is co-administered with nifedipine, atenolol or enalapril, dose adjustment is not required.
  • Unclear interactions
    • ⓘ Nifedipine, atenolol, enalapril.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication of the drug.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

Video instruction

▶

Look at ▶Youtube

Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
• Why do I need to
  • Avoid dangerous prescriptions for your patients.
  • Check the contraindications.
  • Evaluate the safety of therapy in the treatment of children.
  • See the compatibility of drugs with alcohol (enter it as a drug).
  • Point the doctor to the found interaction - you may need to adjust the therapy.
  • Do you need an API for interactions/drug analogues for your project? Write to us.
• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 169,994,378 possible combinations of drugs and their components were found 412,530 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2024-12-19

Category - medicine