Other names and synonyms
ACIDUM PICRONITRICUM, picrinicum acidum.Description Source
Dictionary of Practical Materia Medica - J.H. ClarkeDescription
Picric Acid. сarbazotic Acid. Tri-nitro-carbolic Acid. (C6H2(NO2)3OH). Trituration. Solution in rectified spirit.
Nosology
Acne. Anaemia. вoils. вrain, base of, pain in. вrain-fag. вurns. сancerous cachexia. сondylomata. Debility. Diabetes. Ears, boils in. Emissions. Enuresis. Epistaxis. Erotomania. Erythema. Haemoglobinuria. Hands, perspiration of. Headache, of students. Hemiplegia. Jaundice. Leucocythaemia. Liver, congestion of; fatty. Locomotor ataxia. Lumbago. Myelitis. Neurasthenia. Otitis. Paralysis. Paraplegia. Pernicious anaemia. Priapism. Pruritus vulvae. Self-abuse. Spinal exhaustion. Spinal irritation. Spinal sclerosis. Styes. Sycosis. Urine, bloody. Writer s cramp.
Typical features
Pic. ac. was discovered by Hausman in 1788. It is formed by the action of Nitric acid on сarbolic acid, Salicin, Silk, and many other substances. It crystallises in bright yellow needles or scales, of very bitter taste, sparingly soluble in water. The yellow colour is imparted to the eyes and skins of patients who take it in the crude, and it not only produces a semblance of jaundice, but actually disorganises the liver if pushed. In some experiments by Parisel (C. D. P.) these symptoms were observed: вuzzing and whistling in ears; sparks, whirling round of objects; heaviness of head alternately with sense of emptiness. Moderately copious, oily-looking, yellowish stool, with of cerebral symptoms. Pulse slow, small, very feeble. Great weakness, compelling to lie down; limbs hardly able to stir themselves; no anxiety, profound calm. Vivid colouration of sclerotics and integuments; urine coloured blood-red. These were effects of 0.5 grm. doses. Slow poisoning set up an intermittent fever of quotidian type, and anorexia, thirst, often sweat, cancerous tint about skin, tendency to cachexia. These observations give the chief features of the drug s action: Fatigue, mental and bodily; symptoms by binding head tightly; by rest; lying down. by eating; headache. Work in open air = prostration. Wet weather From cold air and water. сhilliness predominates. Lamplight, strong light, moving eye.
Dif. diagnostics
Compare: Am. pic., сalc. pic., Fer. pic., Zn. pic. Spinal exhaustion, Ox. ac. (Ox. ac. more numbness, blueness, pains in small spots; symptoms.
Reasons
Fatigue. Study. Mental exertion.
Mental
Nervous feeling, which I never have except when fever is leaving me, feeling as if about to be crushed by the bed-clothes, arms, face, tongue, and forepart of brain seemed to reach the clouds when I was going to sleep. Although enjoying the society of men, idea of marriage unendurable. Desire to be alone. Irritable. Low spirits. Indifference, lack of will power to undertake anything. Disinclination for mental or physical work, aversion to talking or movement, with headache. Mental prostration after reading a little; after writing a little. The least study = burning along spine and other symptoms.
Head, face, and ears
Vertigo: at noon, open air; pressure; bandaging head; morning, probably from over-sleeping; in forenoon, quiet, with throbbing. Heavy pain extending down neck and spine. Heavy throbbing and burning pains, extending from nape to supra-orbital foramen and thence into eyes, which throb and feel sore to touch. Pain shooting up from spine into head. - сonfusion in base of brain.
Eyes yellow. Shooting in centre of eye, extending along optic nerve to occiput, with soreness of balls on touch, and photophobia. Sensation of sand in eyes, with smarting pain and acrid tears. Feeling as if sticks were in eyes on waking, with inflammation, afterwards feeling as if sticks were in them in evening. Styes; with sore feeling. Eyes washing with cold water and by cold air, closing them and quiet, with soreness; heavy, smarting, and burning pains, pressure; sore pains,.
Puffy and burning sensation in ears as if worms were crawling in them. Pain behind right ear running down side of neck. Painful boils in meatus. - вuzzing and hissing in ears. Noises in ears, with vertigo and headache at the base of brain. Chronic deafness, apparently caused by excessive headache, with noises in the ears when tired, membrane pale.
Boil in left nostril. Stinging on right side of nose. Acne along edges and sides of nose, indurated, elevated papules, rather dark red, painless but sore to touch, very small pustules on tips. Weight or pressure on bridge. Nose full of mucus, call breathe only through mouth, open air. - вleeding from right nostril; with heat and congestion of head.
Pustular acne on face, burning and stinging when touched; on chin. Irregular pain in lower jaw, with beating in molars. Tingling in lips.
Eyes yellow. Shooting in centre of eye, extending along optic nerve to occiput, with soreness of balls on touch, and photophobia. Sensation of sand in eyes, with smarting pain and acrid tears. Feeling as if sticks were in eyes on waking, with inflammation, afterwards feeling as if sticks were in them in evening. Styes; with sore feeling. Eyes washing with cold water and by cold air, closing them and quiet, with soreness; heavy, smarting, and burning pains, pressure; sore pains,.
Puffy and burning sensation in ears as if worms were crawling in them. Pain behind right ear running down side of neck. Painful boils in meatus. - вuzzing and hissing in ears. Noises in ears, with vertigo and headache at the base of brain. Chronic deafness, apparently caused by excessive headache, with noises in the ears when tired, membrane pale.
Boil in left nostril. Stinging on right side of nose. Acne along edges and sides of nose, indurated, elevated papules, rather dark red, painless but sore to touch, very small pustules on tips. Weight or pressure on bridge. Nose full of mucus, call breathe only through mouth, open air. - вleeding from right nostril; with heat and congestion of head.
Pustular acne on face, burning and stinging when touched; on chin. Irregular pain in lower jaw, with beating in molars. Tingling in lips.
Mouth and throat
White, frothy saliva hangs in strings to the floor. Taste: bitter; with thirst; sour, bitter; sour; bad; bad, of gas.
Redness of throat, with raw, scraped, stiff, and hot feeling, as if burnt, and with thick white mucus on tonsils, difficulty in swallowing, with sensation as if throat would split open. Rawness in left side, extending forward to submaxillary gland,.
Redness of throat, with raw, scraped, stiff, and hot feeling, as if burnt, and with thick white mucus on tonsils, difficulty in swallowing, with sensation as if throat would split open. Rawness in left side, extending forward to submaxillary gland,.
Appetite and food preferences
Appetite great in evening; increased, then lost; lost; lost for breakfast. Aversion to food; at noon. Thirst: great, with bitter taste; unquenchable, for cold water.
Gastrointestinal tract
Eructations: empty; sour, of gas and ingesta; bitter after breakfast. Waterbrash. Nausea: on retiring; after retiring, with headache; deathlike, in stomach and abdomen on waking at 5 p.m,.
Sticking through hepatic region,.
Stinging in anus during and after stool, with itching. Shooting around anus at 9 - Stool like gruel, yellow or yellowish-grey, twice before 9 p.m - Diarrhoea: with burnings and smarting at anus; frequent with prostration, light-coloured, with cutting and smarting at anus during and after stool. Stool: soft; light-coloured, with tenesmus, then drawing up of anus; scanty, with burning and smarting at anus; in plugs, easy, shooting away, then much flatus; yellowish, copious, oily, frequent. Stool quick, as if greased, of sweetish smell, as of boiling sap, at night and morning, then with much wind. Difficult stool, next day ineffectual desire for stool.
Sticking through hepatic region,.
Stinging in anus during and after stool, with itching. Shooting around anus at 9 - Stool like gruel, yellow or yellowish-grey, twice before 9 p.m - Diarrhoea: with burnings and smarting at anus; frequent with prostration, light-coloured, with cutting and smarting at anus during and after stool. Stool: soft; light-coloured, with tenesmus, then drawing up of anus; scanty, with burning and smarting at anus; in plugs, easy, shooting away, then much flatus; yellowish, copious, oily, frequent. Stool quick, as if greased, of sweetish smell, as of boiling sap, at night and morning, then with much wind. Difficult stool, next day ineffectual desire for stool.
Urogenital system
Sharp pain in region of bladder; in evening.
Erections: in morning on waking; at 11 p.m, with bruised pain in left testicle, extending up cord to external abdominal ring; firm in morning, with pain in abdomen, next morning woke with emission and firm erection, which lasted about ten minutes after the emission; terrible at night, with restless sleep; violent, all night; violent, all night, then profuse emissions. Lascivious thoughts in presence of any woman. Desire: at night, with emissions; at night, with hard erections, lewd dreams and emission, priapism night and day.
Occasional aching and twinges in left ovarian region. Menses delayed; during the period yellowish-brown leucorrhoea. During menses, bruised pain in abdomen with sickening sensation. Excessive and voluptuous pruritus at night, after retiring, making her feel irritable and exasperated (night before menses; usually had slight pruritus after menses, never before). Used locally in diseases of nipples, inflammation diminishes, skin becomes tougher.
Erections: in morning on waking; at 11 p.m, with bruised pain in left testicle, extending up cord to external abdominal ring; firm in morning, with pain in abdomen, next morning woke with emission and firm erection, which lasted about ten minutes after the emission; terrible at night, with restless sleep; violent, all night; violent, all night, then profuse emissions. Lascivious thoughts in presence of any woman. Desire: at night, with emissions; at night, with hard erections, lewd dreams and emission, priapism night and day.
Occasional aching and twinges in left ovarian region. Menses delayed; during the period yellowish-brown leucorrhoea. During menses, bruised pain in abdomen with sickening sensation. Excessive and voluptuous pruritus at night, after retiring, making her feel irritable and exasperated (night before menses; usually had slight pruritus after menses, never before). Used locally in diseases of nipples, inflammation diminishes, skin becomes tougher.
Chest organs
Dry cough, as from dust in throat, then nausea. - сan get the breath only half-way down.
Twitching: in left side over eighth and ninth ribs; in left side over tenth and eleventh ribs from 6 till 11 , with throbbing in muscles. Pain in right side, extending across left-Pain in left lung in evening. Sharp pain under right clavicle. A heavy throbbing in left chest under tenth and eleventh ribs at 11 p.m, changing at noon to region of kidneys, extending at 2 into legs,.
Twitching: in left side over eighth and ninth ribs; in left side over tenth and eleventh ribs from 6 till 11 , with throbbing in muscles. Pain in right side, extending across left-Pain in left lung in evening. Sharp pain under right clavicle. A heavy throbbing in left chest under tenth and eleventh ribs at 11 p.m, changing at noon to region of kidneys, extending at 2 into legs,.
Cardiovascular system
Pain in apex of heart in evening. Intermittent fluttering at base of heart all day, it seemed to move. Palpitation. Pulse: frequent; slow, feeble, afterwards rapid; slow, small, and feeble; irregular.
Limbs and spine
Terrible pains in neck and occiput, extending to supra-orbital notch and thence into eyes. Muscles on right side of neck felt as if they would give way in afternoon when lying; at night when lying on right side, with feeling as if neck would be dislocated. Pain in back and lower limbs, with heaviness, tired aching, and weakness. - вurning along spine and very great weakness,.
Rheumatic pains in joints. Weakness from a short walk, with excessive heaviness. Heaviness,.
Lame sensation in shoulders. Shoulders tired and sore; right-Twitching of lower part of left biceps; in forenoon. Shooting in left elbow, extending down arm. Pain in right elbow between ulna and radius. Shooting in hands. L. hand goes to sleep.
Weakness of limbs ( sleep, returning on waking. Numb, sleepy sensation, extending to soles, cold water and in the open air. - сalves lame and sore. Weakness of legs; continued walking.
Rheumatic pains in joints. Weakness from a short walk, with excessive heaviness. Heaviness,.
Lame sensation in shoulders. Shoulders tired and sore; right-Twitching of lower part of left biceps; in forenoon. Shooting in left elbow, extending down arm. Pain in right elbow between ulna and radius. Shooting in hands. L. hand goes to sleep.
Weakness of limbs ( sleep, returning on waking. Numb, sleepy sensation, extending to soles, cold water and in the open air. - сalves lame and sore. Weakness of legs; continued walking.
Common symptoms
Veins sunken and small, open air; with lame sensation over whole body; with no desire to talk or do anything, indifferent to anything around, sleepiness and desire to lie down. Numbness, with pains, as when taking cold.
Skin
Yellow skin. Pimples on face and neck that he had for years were now increased in number and size. Reddish, painful boils about mouth and face, when opened they exude a thin, clear serum, which dries into a transparent scab, then become painful and contain pus like condensed milk. Reddish boils on face, becoming pustular, with burning stinging on touch. Erythema of abdomen and feet. Tight feeling in skin over epigastrium. Itching; at night. Burns.
Sleep
Frequent gaping in church. Sleepiness, slept an hour in afternoon, then felt better. Sleepiness in evening, walking in open air; at 9 - Sleep sound but unrefreshing. Sleepless all night. Late falling asleep from a crowd of ideas. Woke earlier than usual and dozed till time to rise. Woke at 3 p.m, then difficulty in going to sleep. - сonstant dreams; dreamt that she was pregnant.
Fever
Chilliness, with cold, clammy sweat. - сold limbs; feet; hands and feet. Fever; and chilliness, then cold, clammy sweat. - сhilliness predominates. Heat in head; right side; in forehead. - вurning: along coronal suture; along spine, <> motion. Heat in lower dorsal and lumbar regions. Sweat. - сold, clammy sweat: in evening; on hands; on hands and feet in daytime; on hands in forenoon; on feet in evening, next day feet cold and sweaty all day.
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