Compatibility «Cyclosporin» and «Noliprel A»

• Interactions Cyclosporin with Noliprel A

  • Dangerous interactions
    • ⓘ Cyclosporine increases the risk of developing renal dysfunction (hypercreatininemia).
    • ⓘ Several cases of severe glycoside intoxication have been reported within a few days after starting treatment with cyclosporine in patients taking digoxin.
    • ⓘ Some drugs or drugs of other pharmacological classes may increase the risk of hyperkalemia: aliskiren and aliskiren‑containing drugs, potassium salts, potassium-sparing diuretics, ACE inhibitors, angiotensin II receptor antagonists (ARA II), heparin, immunosuppressants such as cyclosporine or tacrolimus, trimethoprim, drugs containing co-trimoxazole (trimethoprim + sulfamethoxazole).
  • Negative interactions
    • ⓘ Some drugs or classes of drugs may increase the incidence of hyperkalemia: aliskiren, potassium salts, potassium‑sparing diuretics, ACE inhibitors, ARA II, NSAIDs, heparins, immunosuppressants (such as cyclosporine or tacrolimus), trimethoprim and drugs containing co-trimoxazole (sulfamethoxazole + trimethoprim).
    • ⓘ Caution should be exercised when using cyclosporine together with potassium-sparing drugs (potassium-sparing diuretics, ACE inhibitors, angiotensin II receptor antagonists) or drugs containing potassium, since with their simultaneous use with cyclosporine, severe hyperkalemia may develop.
    • ⓘ The use of potassium-sparing diuretics (in pm spironolactone, amiloride, triamterene), potassium supplements or other drugs capable of increasing serum potassium levels (in pm indomethacin, heparin, cyclosporine) may increase the risk of hyperkalemia.
  • Positive interactions
    • ⓘ It is possible to increase the concentration of creatinine in blood plasma without changing the concentration of cyclosporine in blood plasma, even with a normal content of water and sodium ions.
    • ⓘ It is possible to increase the concentration of creatinine in blood plasma without changing the concentration of circulating cyclosporine, even with a normal content of liquid and sodium ions.
  • Unclear interactions
    • ⓘ Cyclosporine, tacrolimus.

Decoding the colors of interactions and contraindications

Dangerous	—	a pronounced negative interaction or contraindication.
Negative	—	negative interaction or side effect that may reduce effectiveness.
Positive	—	the interaction can SOMETIMES be used as a positive (often a dose adjustment is needed), or it is an indication.
No	—	the drugs do NOT interact, which is separately indicated in the instructions.
Unclear	—	the system failed to pre-assess the danger.

Video instruction

▶

Look at ▶Youtube

Additional information

• Kiberis checks interactions and evaluates drug compatibility for free online right in the instructions thanks to the latest artificial intelligence technologies. The accuracy of finding is more than 95%, the accuracy of the hazard assessment is more than 80%. The online medical service takes into account all the drug groups of the selected drugs and all their components. And since the database contains 25,000 drugs with detailed instructions, not every pharmacologist can compete with our artificial intelligence. List of popular interactions.
• Why do I need to
  • Avoid dangerous prescriptions for your patients.
  • Check the contraindications.
  • Evaluate the safety of therapy in the treatment of children.
  • See the compatibility of drugs with alcohol (enter it as a drug).
  • Point the doctor to the found interaction - you may need to adjust the therapy.
  • Do you need an API for interactions/drug analogues for your project? Write to us.
• The use of information about interactions is only possible as an introduction. This information should not be used to adjust therapy without consulting a specialist.
• The article is written: artificial intelligence Kiberis
• Sources: official instructions for medicines and their active substances, as well as inter-group interactions described in medical studies and textbooks.
• Total analyzed: 170,043,367 possible combinations of drugs and their components were found 412,579 interacting combinations.
• Medicine section: Standard evidence-based medicine
• The date of the last update of the interaction database: 2026-07-09

Category - medicine